I'm running 1.0alpha5 on my home server, and have it set up for one user. You can check it out at status.ritchiewilson.com.
Locally everything runs fine (can login, add messages, connect from android, etc) but I try subscribing to users and groups on identi.ca and it fails, with identi.ca telling me "Couldn't confirm remote profile address." I'm just trying to join a group with the handle 'firstname.lastname@example.org'.
Has anyone run into this?